ITK is an open-source, cross-platform system that provides developers with an extensive suite of software tools for image analysis.
Developed through extreme programming methodologies, ITK employs leading-edge algorithms for registering and segmenting multidimensional data. It is widely used and contributed in the medical imaging field.
Highly optimized C++, well commented Consistently updated (new) algorithms many tools and softwares are built upon it connected with VTK Insight Journal (open code and sample data) Extensive list of examples & tutorials
yet detached from the bioimage analysis world hard to use for end users without development skills